Below are the most common reasons that can cause IVF not to work in general. Remember for details information you need to talk to the top fertility doctors and check with a lot of medical tests.
| Reason for IVF Failure | Description |
| Embryo Implantation Failure | The embryo is unable to attach to the uterine lining. |
| Poor Egg Quality/Sperm Quality | Low-quality eggs or sperm affect fertilization and embryo development. |
| Endometrial Receptivity Issues | Problems with the uterine lining prevent successful implantation. |
| Hormonal Imbalances | Disruptions in hormones can affect ovulation and uterine preparation. |
| Uterine Abnormalities | Structural issues like fibroids, polyps, or congenital anomalies can hinder success. |
| Age Factors | Advanced maternal age significantly decreases egg quality and quantity. |
| Genetic Factors | Chromosomal abnormalities in embryos can lead to failed implantation or miscarriage. |
| Immune System Issues | Autoimmune disorders may cause the body to reject the embryo. |
| Infections | Infections in the reproductive system can impede implantation and embryo development. |
| Lifestyle Factors | Smoking, excessive alcohol consumption, obesity, and poor diet can negatively impact fertility. |
Read more: IVF in another country
In following, we talk about the most common reasons for when IVF doesnt work! And at end we discuss where you can do IVF with High sucess rate and internation standard technologies at affrodabe cost.
Reasons for IVF Failure
Reason 1: Embryo Implantation Failure
One of the most common reasons for IVF failure is the inability of the embryo to implant successfully in the uterine lining. This can occur due to various factors, including:
- Unhealthy embryos: Chromosomal abnormalities can prevent embryos from developing properly, leading to unsuccessful implantation or early miscarriage.
- Uterine conditions: Polyps, fibroids, or a thin endometrial lining can hinder implantation. Infections or inflammation in the uterus may also play a role.
Read more: Best country for IVF in Asia
Reason 2: Poor Egg or Sperm Quality
The quality of eggs and sperm is crucial for successful fertilization and embryo development. Factors affecting quality include:
- Age: As women age, the quality and quantity of their eggs decline, significantly impacting IVF success rates. For instance, women over 40 have a much lower success rate than those under 35.
- Sperm abnormalities: Poor sperm quality can also lead to fertilization issues and affect embryo viability.
Read more: When IVF is Needed ?
Reason 3: Endometrial Receptivity Issues
The receptivity of the endometrium (the uterine lining) is vital for embryo implantation. Factors contributing to receptivity problems include:
- Hormonal imbalances: Insufficient progesterone levels can prevent the endometrium from adequately preparing for implantation.
- Underlying conditions: Conditions like endometriosis or scarring in the uterus can compromise receptivity, making it difficult for embryos to implant successfully.
What Can You Do If IVF Doesn’t Work?
If IVF fails, it’s essential to consult with a top fertility specialist who can analyze the reasons behind the failure and suggest appropriate next steps. Options may include:
- Further testing: Genetic testing of embryos, hormonal assessments, and evaluations of uterine health can provide insights into potential issues.
- Lifestyle changes: Improving overall health through diet, exercise, and stress management may enhance fertility.
- Consider alternative treatments: Options such as donor eggs or sperm, surrogacy, or adoption may be viable paths forward.
As we mentioned above, consulting with a doctor before IVF will prevent failure and help you avoid wasting money on medical procedures.
Read more: What are the steps before IVF?
What is the Next Treatment After IVF Failure?
Following an unsuccessful IVF cycle, couples often consider several options:
- Repeat IVF cycles: Some may try another IVF cycle with adjustments based on previous outcomes.
- Other assisted reproductive technologies (ART): Techniques such as intracytoplasmic sperm injection (ICSI) or preimplantation genetic testing (PGT) might be recommended.
- Exploring surrogacy or adoption: If repeated attempts at IVF fail, these alternatives might be considered as fulfilling paths to parenthood.
Read more: How do you get pregnant through IVF?
| Next Treatment Options | Description |
| Repeat IVF Cycle | Retry the IVF process with adjustments based on the previous cycle analysis. |
| Intracytoplasmic Sperm Injection (ICSI) | A specialized form of IVF where a single sperm is injected directly into an egg, useful for sperm issues. |
| Egg Donation | Utilizing donor eggs if the quality of the woman’s eggs is a concern. |
| Embryo Adoption | Adopting embryos created by another couple is suitable for those with significant fertility issues. |
| Additional Testing | Conduct further tests to identify underlying issues, such as genetic testing or uterine evaluations. |
| Lifestyle Changes | Implementing healthier lifestyle choices to improve overall fertility health. |
| Consultation with a Different Clinic | Seeking a second opinion or switching clinics for better success rates. |
| Consider Surrogacy | If carrying a pregnancy is not feasible, surrogacy may be an option to explore. |
Read more: IVF success rate in Iran
Where Should You Have IVF to Minimize the Risk of Failure?
Choosing the right clinic is crucial for maximizing success rates in IVF treatments. Iran has emerged as a notable destination for fertility treatments due to its high-quality services and affordability. Key features include:
- Expertise and facilities: Iran boasts numerous reputable fertility centers, such as Royan Institute and MOM Fertility Center, which are known for their advanced technologies and experienced specialists.
- Cost-effectiveness: IVF costs in Iran range from $1,200 to $3,500, making it more accessible than many Western countries.
- Comprehensive care: Many clinics offer services beyond standard IVF procedures, including genetic testing and personalized treatment plans tailored to individual needs.
In conclusion, IVF failure can be disappointing, but couples can feel more confident in their efforts to become parents if they know why it happened and look into other choices.
Read more: Best IVF centers in Iran
IranHealthAgency can help you during the process, ensuring it will be smooth. We help you with:
| Service | Description |
| Free Consultation | Initial assessment to understand unique needs and tailor treatment plans. |
| Comprehensive Fertility Testing | Extensive testing to evaluate fertility issues for both partners. |
| Advanced Genetic Screening (PGD/PGS) | Preimplantation genetic diagnosis and screening to identify genetic abnormalities in embryos. |
| Personal Assistant & VIP Transfer | Dedicated support throughout the treatment journey, including transportation services. |
| Hotel Accommodation | Arrangements for comfortable lodging during the treatment period. |
| Planning All Operations | Experienced professionals coordinate all medical procedures from start to finish. |
| Multilingual Support | Assistance in multiple languages (e.g., English, Arabic) to facilitate communication and understanding. |
| Access to Top IVF Clinics | Collaboration with leading fertility centers in Iran, ensuring high-quality care and advanced technology. |
| Patient-Centered Care | Emphasis on personalized treatment plans tailored to individual needs and conditions. |
Read more: IVF in Iran
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